Everyone knows the saying that "medicine is three parts poison". Medicine can both cure diseases and harm people. Xue Shan Yi Zhi Hao is such a medicine, so it should be used with caution. Let's take a look at it with the editor!
Xue Shan Yi Zhi Hao
Preparation of Xue Shan Yi Zhi Hao
1. Collection
In September to October, the roots are dug up, the fibrous roots are removed, washed, sliced, and dried in the sun.
2. Processing
Soak the Xue Shan Yi Zhi Hao in cold water, changing the water 2-3 times a day, until there is no numbness or spiciness when tasted. Remove it from the water, and then cook it with licorice and black beans until there is no white core inside. Finally, take it out and dry it.
Functions and indications of Xue Shan Yi Zhi Hao
It has anti-inflammatory and analgesic effects, and can dispel wind and dampness.
1. Treatment of bruises, rheumatism, and toothache
Take 0.25 grams of Xue Shan Yi Zhi Hao orally (about the size of a grain of rice).
Xue Shan Yi Zhi Hao
2. Treatment of bruises, snake bites, and insect bites
Soak 5 grams of Xue Shan Yi Zhi Hao in one kilogram of liquor for ten days, and then apply it externally (do not take it internally).
Toxicity of Xue Shan Yi Zhi Hao
It is warm in nature, bitter and numbing in taste, and highly toxic.
Processing of Xue Shan Yi Zhi Hao
Soak the Xue Shan Yi Zhi Hao in cold water, changing the water 2-3 times a day, until there is no numbness or spiciness when tasted. Remove it from the water, and then cook it with licorice and black beans until there is no white core inside. Finally, take it out and dry it.
The main component of Xue Shan Yi Zhi Hao is Aconitine.
Also known as: Fu Zi Jing
Molecular formula: C34H47NO11
Molecular weight: 645.74
Xue Shan Yi Zhi Hao
It is a kind of diterpene alkaloid. It exists in various plants of the Aconitum genus, such as Aconitum carmichaelii, Aconitum kusnezoffii, Aconitum austroyunnanense, and Aconitum sinomontanum. It is a colorless transparent crystal with a melting point of 204℃ and a specific rotation of +19° (chloroform). It is soluble in chloroform, benzene, ethanol, etc. Aconitine is an ester that easily hydrolyzes to lose one molecule of acetic acid, thereby reducing its toxicity. Further hydrolysis removes one molecule of benzoic acid to produce aconine, which is only 1/2000 to 1/4000 as toxic as aconitine.
Traditional Chinese medicine has found that the toxicity of the side root of Aconitum (the root of Aconitum carmichaelii) is reduced after processing, which may be related to the reduced toxicity of aconitine after hydrolysis. Aconitine has analgesic effects on various neuralgia and gout, but due to its high toxicity, it is no longer used clinically. Chinese medicine and folk medicine widely use various Aconitum species to relieve fever and pain, and treat rheumatism and stubborn joint pain. However, since Aconitum species often contain aconitine, caution must be exercised when using them. The lethal dose of aconitine (oral) is 0.2 milligrams, and the lethal dose is 2.5 milligrams. Chinese medicine uses mung beans or honeysuckle to detoxify.
