The Toxicity of Qingmuxiang in Chinese Herbal Medicine: A Closer Look at its Contraindications

December 29, 2023

Chinese herbal medicine Qingmuxiang has a slight toxicity. It is the root of Aristolochia debilis and Aristolochia heterophylla, which belong to the Aristolochiaceae family. Although Qingmuxiang has the effects of promoting qi circulation, relieving pain, detoxifying, and reducing swelling, its toxicity to the kidneys cannot be ignored. Therefore, it is rarely used in traditional Chinese medicine nowadays. Let's take a look at the contraindications of Qingmuxiang!
 


 

  [Reasons for the Contraindications of Qingmuxiang]

  The reason why Qingmuxiang is contraindicated is because it has a very strong nephrotoxicity. Qingmuxiang contains aristolochic acid, which can cause severe toxic side effects such as acute renal failure and acute tubular necrosis.

  In fact, as early as 2004, it has attracted great attention from the country, and in 2004, the use of "Guangfangji" and the root of Aristolochia debilis and Aristolochia heterophylla, which have higher content of aristolochic acid in the Aristolochiaceae family, were banned.

  In addition, the National Medical Products Administration officially issued a document stating that Chinese medicine preparations containing "Qingmuxiang" have been discontinued due to their potential adverse reactions such as kidney damage. Such medicines will be eliminated from the market of medicinal materials.

  Now, Qingmuxiang is replaced by Guangmuxiang in prescription. If it is necessary to use Qingmuxiang, it should still be used under the guidance of a qualified physician, with strict control of dosage and treatment course.

  During the treatment, attention should be paid to the monitoring of renal tubular and glomerular function. However, it should be used with caution in children and the elderly, and pregnant women, infants, young children, and those with renal insufficiency should not take it.
 


 

  [Contraindications of Qingmuxiang]

  1. It has slight toxicity. It is used in folk medicine to treat abdominal pain. In clinical practice, it is also used in small doses to treat stomach pain and abdominal pain.

  A slightly larger dose can cause nausea and vomiting. Long-term use can cause kidney toxicity.

  Therefore, it is now rarely used to treat hypertension. The National Medical Products Administration has canceled its medicinal standards.

  2. It should be used with caution in patients with deficiency-cold syndrome.

  "Tang Bencao" states, "Do not use it excessively, as it can cause persistent vomiting and diarrhea."

  "Benjing Fengyuan" states, "For lung cold cough, cold phlegm causing asthma, and stomach deficiency with poor appetite, it is not suitable to use it, as it has a pungent and aromatic nature that can spread rapidly."

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