Avoid Mixing Milk with Medication: Impact on Efficacy and Health

December 22, 2023

In modern families, only children make up a large proportion. Some parents, in order to make their children willing to take medicine, often crush the medicine and mix it with milk or give it with milk. Although this solves the problem of children being willing to take medicine, it ignores the effect of milk on the medicine, affecting the efficacy of the medicine.


Do Not Use Milk to Administer Medicine

Milk contains various substances that make it difficult for drugs to be absorbed by the gastrointestinal tract. Milk can easily form a film on the surface of the medicine, causing chemical reactions between the minerals such as calcium and magnesium in the milk and the medicine, resulting in insoluble substances that affect the release and absorption of the medicine.

Some drugs can even be destroyed by the ions in milk, reducing the concentration of the drug in the blood and affecting the course of treatment. Therefore, do not drink milk before or after taking medicine for one hour. Which drugs should not be taken with milk? In daily life, some patients take medicine with milk or drink milk shortly after taking medicine. In fact, the interval between taking certain drugs and drinking milk should not be too short, let alone taking them together with milk.

Pharmacists in drugstores must remind customers of this when they buy medicine.

These drugs include: antibiotics, such as tetracycline, streptomycin, erythromycin, etc.


These drugs can form complexes with calcium ions in milk in the intestines, reducing drug absorption, reducing efficacy, and even causing complete failure of the drug. Antihypertensive drugs: Severe hypertensive patients who take antihypertensive drugs such as Nifedipine while drinking milk or eating dairy products may cause a sudden increase in blood pressure. In severe cases, blood pressure may continue to rise, and even hypertensive crisis may occur. Cardiotonic drugs: Heart failure patients who take digitalis, digoxin, and other drugs with milk are prone to poisoning reactions and even accidents because the calcium in milk can enhance the toxicity of cardiac glycosides (digitalis, digoxin).

Iron-containing drugs: Iron-deficiency anemia is a common disease in women and children.

Calcium ions in milk can compete with iron preparations for absorption in the duodenum, reducing the absorption of iron preparations and reducing their efficacy. Therefore, some patients do not respond to long-term use of iron preparations, and one of the reasons is the simultaneous use of milk.

Antipsychotic drugs: When schizophrenic patients take antipsychotic drugs, or children with rickets take calcium powder or calcium tablets, drinking milk, breastfeeding, yogurt, or cheese can reduce the efficacy of the drugs. In addition, milk itself contains calcium. Using it to administer tablets or other drugs can easily cause calcification in the gastrointestinal tract, leading to the loss of drug efficacy. In severe cases, gallstones and kidney stones may even form. Therefore, milk should be avoided as much as possible when administering medication, and infants should wait for a period of time before breastfeeding after taking medication.

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