Chronic Aplastic Anemia is a group of comprehensive diseases characterized by the proliferation and differentiation disorders of bone marrow multipotent stem cells, resulting in a decrease in total red bone marrow capacity, exhaustion of hematopoietic storage function, and a decrease in total blood cells. It is generally difficult to cure and has a poor prognosis. The clinical treatment usually uses Kangli Long, but Kangli Long has certain side effects, which doctors will consider repeatedly when used clinically. Today, I will introduce to you the recommendation of Professor Wei Keming, a famous traditional Chinese medicine doctor - Xue Zhangping. Professor Wei believes that Xue Zhangping has significant therapeutic effects and minimal side effects in the treatment of chronic aplastic anemia. Let's take a look!
Professor Wei Keming is a famous traditional Chinese medicine doctor in Zhejiang Province and has been engaged in the prevention and treatment of blood diseases for decades. His research on Xue Zhangping tablets, made from the extract of the traditional Chinese medicine silkworm sand - chlorophyll derivative chlorophyll copper sodium salt, has been used to treat chronic aplastic anemia. The results showed that the therapeutic effect of Xue Zhangping was significantly better than that of the Western medicine control group.
Kangli Long is a androgenic drug that has been used to treat aplastic anemia for more than 30 years. Its mechanism is to promote protein synthesis, inhibit protein synthesis, alleviate bone marrow suppression, promote the production of erythropoietin (EPO) by the kidneys, and make stem cells enter the G1 phase from the G0 phase, thereby entering the cell proliferation cycle to provide more EPO-sensitive cells and restore hematopoiesis. Kangli Long's anabolic effect is stronger than its androgenic effect.
Traditional Chinese medicine silkworm sand is warm in nature, with a sweet and spicy taste, and enters the liver and spleen meridians. It has the effects of clearing heat and dispelling wind, promoting blood circulation and dredging collaterals, promoting diuresis and resolving dampness, and calming and sedating. According to Chen Cangqi's "Materia Medica Collection" from the Tang Dynasty, "late silkworm sand treats blood stasis," and Luo Longji's "Internal Medicine Collection" from the Song Dynasty records, "late silkworm sand treats blood stasis and blood deficiency." Ye Gui's "Renewed Materia Medica" and Zhao Qiguang's "Original Materia Medica" from the Qing Dynasty both record "late silkworm sand treats blood deficiency and cannot nourish meridians."
Xue Zhangping tablets: Professor Wei Keming used modern scientific concepts to extract chlorophyll from silkworm sand using advanced techniques, and then complexed it with copper (Cu2+) to produce chlorophyll copper sodium salt. The molecular weight is 68421 Da, and the basic structure is a porphyrin ring composed of four pyrrole rings, which is extremely similar to the structure of hemoglobin and can participate in hemoglobin synthesis, promote blood production, and act as a good hematopoietic cell composite agent. It has achieved good therapeutic effects in the treatment of aplastic anemia and has made beneficial explorations for the combined treatment of traditional Chinese and Western medicine.
The etiology of aplastic anemia is related to the deficiency of the trace element copper. Copper ions can promote bone marrow hematopoiesis. Ceruloplasmin is a protein that transports copper in human and mammalian plasma. Clinical side effects include facial flushing, burning sensation, palpitations, nausea, rash, and lower limb edema. This medicine is a hematopoietic factor that promotes hematopoiesis and can also increase the activity of erythropoietin synthesis, stimulate the proliferation of erythroid precursor cells, and reduce iron utilization disorders caused by hematopoietic disorders. A large number of clinical studies and experiments have shown that apart from causing green stool, no toxic side effects have been found. Liver and kidney function tests before and after treatment did not show any changes.
The above is the complete content of Xue Zhangping tablets for the treatment of chronic aplastic anemia discovered by Professor Wei Keming. I hope it can provide treatment references and new hope for patients with chronic aplastic anemia!
