Pregnant women are advised to choose effective and relatively safe medications for their unborn babies, control the dosage, and avoid combining medications if possible. Non-essential medications should be avoided, especially during the first trimester. Before taking any medication, carefully read the instructions and consult with a doctor or pharmacist to ensure its safety. In cases where a serious illness threatens the life of the mother and requires the use of teratogenic drugs, priority should be given to saving the patient's life. Here are some teratogenic drugs commonly used:
Antibiotics: Most antibiotics can pass through the placenta and enter the fetus, such as streptomycin, kanamycin, and kanamycin. These drugs may affect the fetus's auditory nerve. Sulfonamides, tetracyclines, and other drugs can cause congenital malformations in the fetus and should be avoided. Penicillin and cephalosporins are relatively safer.
Antiviral drugs: Ribavirin, also known as ribavirin, has been shown to cause teratogenic and embryocidal effects in almost all tested animals. Combination preparations containing this drug should be avoided by pregnant women. Acyclovir and ganciclovir are effective antiviral drugs for herpes simplex virus, but their antiviral mechanism is still unclear, so they should only be used in cases where the mother has life-threatening disseminated herpes. Generally, this drug should be avoided. Amantadine, used to treat viral infections, should also be avoided by pregnant women.
Antifungal drugs: Amphotericin B should be the preferred drug for deep fungal infections during pregnancy, but caution should still be exercised, especially during the first trimester. Topical drugs commonly used to treat fungal vaginitis, such as miconazole, should also be used with caution.
Antihypertensive drugs: Diuretics should not be used during pregnancy to prevent blood concentration and reduce effective circulating blood volume. Atenolol and methyldopa are not recommended. Magnesium sulfate should not be used as an antihypertensive drug. ACE inhibitors and angiotensin II receptor antagonists are prohibited.
Antidiabetic drugs: The use of oral antidiabetic drugs in pregnant women lacks research, so insulin is recommended for pregnant women who fail to achieve blood glucose control through lifestyle interventions.
