Guanmutong Poisoning: The Role of Gastric Lavage and Treatment Options

March 14, 2024

The herb Guanmutong is widely used in the traditional Chinese medicine Longdan Xiegan Wan. It is a nephrotoxic herb that was previously used in the treatment of many diseases. Can gastric lavage be used for Guanmutong poisoning?


Image of Guanmutong

Can gastric lavage be used for Guanmutong poisoning?

Gastric lavage and enema, according to reports, can delay the progression of the disease when corticosteroids are administered in the early stages. Timely hemodialysis can achieve favorable treatment outcomes.

For patients with significantly impaired renal function who have reached end-stage renal disease, replacement therapy such as kidney transplantation may be necessary.

Symptoms of Guanmutong poisoning

The toxic component in Guanmutong is aristolochic acid, which can cause acute renal failure and even death when taken in excessive amounts.

Symptoms of poisoning include discomfort in the upper abdomen, followed by vomiting, headache, chest tightness, abdominal distension and pain, diarrhea, facial swelling, frequent urination, urgency to urinate, gradual onset of generalized edema, and altered mental state.

Causes of Guanmutong poisoning

Overdose and long-term use are the main causes. Therefore, it is crucial to strictly follow the recommended dosage and usage.

Guanmutong contains aristolochic acid, which is highly toxic to the kidneys and can impair renal tubular function, leading to renal failure. Despite the different names used to describe the events, they refer to almost the same thing due to their close relationship.

The toxic component in Guanmutong is aristolochic acid, which can cause acute renal failure and even death when taken in excessive amounts.

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