Diangui’ainaxiang: A Herbal Remedy for Menstrual Disorders and Blood Stasis

March 10, 2024

  [Introduction]

  

  Diangui’ainaxiang HERBA BLUMEAE RIPARIAE, also known as the dried whole herb of Blumea riparia (L.) DC., is a plant of the Asteraceae family. It is harvested in summer and autumn and dried in the shade. The rhizome of this herb is enlarged, with a diameter of 1-3cm. The surface is brownish-brown or brownish-yellow, with 2 to several stem bases, and the lower part of the root is curved like a conical shape. It has fine roots and longitudinal wrinkles, and prominent punctate pores can be seen. The stem is slender and cylindrical, with a diameter of 3-7mm. It branches in the upper part and has a purple-brown or gray-green surface with longitudinal ridges and a slightly hard texture. The pith is well-developed, white, and the old stem wood is radiate. The leaves are opposite, often curled or fragmented, and become elliptical when flattened, with a length of 3-7cm and a width of 1.5-4cm. The margin has dotted serrations, and the leaf color is gray-green or dark green, with a slightly crisp texture. Some have head-shaped inflorescences. It has a slight aroma and a mild taste.

  

  [Identification]

  

  (1) Transverse section of the root: The cork layer consists of several layers of cells. The cortex consists of several layers of cells, among which secretory cavities or fissures can be seen. The phloem is slightly wider and mostly triangular in shape, and the phloem fibers have thin walls and are mostly arranged longitudinally. The xylem is radiate, with oval-shaped vessels with a diameter of 45-165μm, mostly existing individually or arranged in 2-4 longitudinal rows, and 2-10 rows of ray cells, some of which are fissure-like. Transverse section of the stem: The slice is bluntly round-toothed. The cork layer consists of several layers of cells, and the cortex is compressed into 1-3 layers of cells at the angles. The cells between the two phloem bundles are loose, and there are scattered single elongated stone cells and secretory cavities. The medullary sheath fiber bundles are semi-circular at the angles, often converging from several tens of fibers, the phloem is triangular, the phloem fibers are scattered, the cell walls are thin, and the cell cavities are large. The xylem is radiate, with circular vessels with a diameter of 90-208μm, mostly existing individually or in 2-3 parallel, and 2-8 rows of ray cells. The medullary cells are circular.

  
         

 

  (2) Take 5g of the powder of this herb, add 30ml of petroleum ether (60-90°C), soak for 24 hours, filter, evaporate the filtrate on a water bath, dissolve it with 1ml of ethanol, and use it as the test solution. Take 5g of the reference herb of Diangui’ainaxiang, and make the reference herb solution in the same way. Perform thin-layer chromatography according to the method described in the appendix VI B of the Chinese Pharmacopoeia. Take 5μl of each of the above solutions, spot them on the same silica gel G thin-layer plate, and use toluene-acetic acid ethyl ester (12:1) as the developing agent. After development, take out the plate, dry it, and spray it with phosphomolybdic acid reagent. Heat it at 105°C until the spots show clear color. In the chromatogram of the test solution, at the corresponding position to the chromatogram of the reference herb, spots with the same color appear.

  

  [Inspection]

  

  Moisture: Determined by the method described in appendix IX H of the Chinese Pharmacopoeia, it should not exceed 14.0%.

  

  [Processing of this herb]

  

  Remove impurities, cut into segments, and dry in the shade.

  

  [Nature, Taste, and Meridians]

  

  Light and neutral. It belongs to the liver and spleen meridians.

  
         

 

  [Functions and Indications]

  

  Activates blood circulation and resolves blood stasis, stops bleeding and regulates menstruation. It is used for excessive menstruation, prolonged menstrual period, and postpartum lochia retention caused by blood stasis.

  

  [Usage and Dosage]

  

  10-30g. For external use, use an appropriate amount.

  

  [Storage]

  

  Store in a dry and cool place.


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