The Toxicity and Contraindications of Qingmuxiang: A Traditional Chinese Medicine with Kidney Risks

February 27, 2024

Chinese medicine Qingmuxiang has a slight toxicity. It is the root of the Aristolochia plant, which belongs to the Aristolochiaceae family. Although Qingmuxiang has the effects of promoting blood circulation, relieving pain, detoxifying, and reducing swelling, its toxicity to the kidneys cannot be ignored. Therefore, it is rarely used in traditional Chinese medicine nowadays. Let's take a look at the contraindications of Qingmuxiang below!


The reason why Qingmuxiang is prohibited is because it has a strong nephrotoxicity. Qingmuxiang contains aristolochic acid, which can cause serious toxic side effects such as acute renal failure and acute tubular necrosis.

In fact, as early as 2004, it has attracted high attention from the country, and in 2004, the plants "Guangfangji" and the roots of Aristolochiaceae plants Aristolochia and Asarum heterotropoides var. mandshuricum with high content of aristolochic acid were prohibited.

In addition, the State Food and Drug Administration officially issued a document stating that traditional Chinese medicine preparations containing "Qingmuxiang" have been cancelled their medicinal standards due to their potential adverse reactions such as kidney damage. Such medicines will be eliminated from the market.

Now, Qingmuxiang is replaced by Guangmuxiang in prescription. If it is necessary to use Qingmuxiang, it should be used under the guidance of a qualified physician, with strict control of dosage and treatment course.

During the treatment, the monitoring of renal tubular and glomerular function should be paid attention to. However, it should be used with caution in children and the elderly, and it should be prohibited for pregnant women, infants, young children, and those with impaired kidney function.

1. Qingmuxiang has slight toxicity. It is commonly used in folk medicine to treat abdominal pain. It is also used in clinical practice in small doses to treat stomach pain and abdominal pain.

Larger doses can cause nausea and vomiting. Long-term use can cause kidney toxicity.

Therefore, it is rarely used to treat hypertension. The National Medical Products Administration has canceled its medicinal standards.

2. It should be used with caution in patients with deficiency-cold.

"Tang Bencao": "It should not be taken in large quantities, as it causes persistent vomiting and diarrhea."

"Ben Jing Feng Yuan": "For lung cold cough, cold phlegm causing wheezing, and stomach deficiency with loss of appetite, do not take it, as it has the effect of dispersing cold and spreading fragrance."

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