The Medicinal Benefits and Toxicity of Tie Shu Guo: A Double-Edged Plant

February 5, 2024

Tie Shu Guo is a common ornamental plant in many scenic areas. Its leaves can be used as medicine to treat various diseases. However, we need to know that Tie Shu Guo is highly toxic and eating it raw can lead to poisoning.


【The Efficacy and Function of Tie Shu】

1. Leaves: Tie Shu leaves have the functions of astringing and stopping bleeding, detoxifying, and relieving pain. They are used for various conditions such as bleeding, gastritis, gastric ulcers, hypertension, neuralgia, amenorrhea, and cancer.

2. Flowers: Tie Shu flowers have the functions of regulating qi, relieving pain, nourishing the kidneys, and securing essence. They are used for stomach pain, nocturnal emission, leucorrhea, dysmenorrhea, and other conditions.

3. Fruits: Tie Shu fruits have the functions of clearing heat, stopping bleeding, and resolving phlegm. They are used for cough, dysentery, and wounds from falls and cuts.

4. Roots: Tie Shu roots have the functions of dispelling wind, activating collaterals, and nourishing the kidneys. They are used for conditions such as pulmonary tuberculosis with hemoptysis, kidney deficiency with toothache, lumbago, leucorrhea, rheumatic joint numbness and pain, and injuries from falls and blows.


【Pharmacological Effects of Tie Shu Fruits】

1. Carcinogenic effects

Since the discovery in 1962 that feeding rats with food mixed with su tien glycosides can cause tumors in the liver and kidneys, su tien glycosides have been synthesized as carcinogens. They can metabolize into heavy nitro methane in the body and have carcinogenic effects on various cells.

2. Neurotoxicity

Eating Tie Shu fruit seeds can cause paralysis and often leads to muscular atrophy spinal lateral sclerosis. There is demyelination in the fasciculus gracilis and spino-cerebellar tracts, as well as deposits of osmium-loving substances. However, no abnormal lesions have been found in the central nervous system of rats.


【Toxicity of Tie Shu Fruits】

1. Carcinogenicity

Although Tie Shu fruits are highly valuable medicinal materials, they also have a certain level of toxicity, especially in terms of carcinogenicity. This is because Tie Shu fruits contain a large amount of natural su tien glycosides, which are natural carcinogenic substances. After entering the human body, they can increase the burden on the liver and kidneys, and promote the generation of carcinogens in the body, significantly increasing the incidence of cancer.

2. Neurotoxicity

Tie Shu fruits are highly toxic and can directly affect the human nervous system. They can cause neurological paralysis and muscle atrophy.

In addition, after eating Tie Shu fruits, people may experience symptoms of poisoning such as dizziness, vomiting, and abdominal pain. In such cases, it is necessary to stop taking them and seek medical treatment if the symptoms are severe.

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