The plant known as Da Wei Yao is the whole herb or root of the plant Da Wei Yao, which belongs to the family Rubiaceae. It is mainly found in Fujian, Taiwan, Guangdong, Hainan, Guangxi, and Yunnan provinces in China. Da Wei Yao has the effects of clearing heat, detoxifying, and diuresis. It can be used to treat pneumonia, empyema, sore throat, oral ulcers, bladder stones, and abscesses, among other conditions.
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【Effects and Uses of Da Wei Yao】
Traditional Chinese medicine believes that Da Wei Yao has the effects of clearing heat, detoxifying, and diuresis. It is commonly used to treat pneumonia, empyema, sore throat, oral ulcers, bladder stones, and abscesses.
1. "Fujian Folk Herbal Medicine": "Diuretic, heat-clearing, abscess-resolving, detoxifying. Used for fever with rash, pneumonia, empyema."
2. "Nanning Medicinal Records": "Anti-swelling, detoxifying, dispersing accumulations. Internally used to treat bladder stones; branches and leaves are boiled with lime water for fumigation and treatment of snakehead sores."
3. "Folk Herbal Medicine in Southern Fujian": "Used to treat sore throat, cough, early-stage abscesses, and oral ulcers."
4. "Folk Herbal Medicine in Southern Fujian": "Used to treat dysmenorrhea, irregular menstruation, and whole body pain during menstruation."
5. "Compilation of Chinese Herbal Medicine": "Heat-clearing, detoxifying. Mainly used for pneumonia, lung abscess, empyema, diarrhea, dysentery, orchitis, diphtheria, oral ulcers, and abscesses."
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【Pharmacological Effects of Da Wei Yao】
1. Anti-cancer effects:
The anti-cancer active components isolated from Da Wei Yao are Da Wei Yao alkaloid and Da Wei Yao alkaloid N-oxide. Da Wei Yao alkaloid has a 16-fold effectiveness against mouse leukemia P388.
2. Effects on smooth muscle:
The water extract of the root can increase the tension of the isolated rabbit duodenum, but has no significant effect on the isolated guinea pig ileum; the alcohol extract has inhibitory effects on both. Both the water and alcohol extracts have a oxytocin-like effect.
3. Other effects:
The water extract of the root can decrease blood pressure and cause respiratory stimulation when intravenously injected into anesthetized cats; it has an inhibitory effect on the isolated toad heart; the alcohol extract has no effect.
When Da Wei Yao alkaloid N-oxide is intravenously injected into dogs at a dose of 1500mg/kg, it increases heart rate, decreases left ventricular end-diastolic pressure and cardiac output, slightly decreases pulmonary vascular resistance, and slightly increases systemic vascular resistance.
The Tianjiecai alkaloid isolated from Da Wei Yao seeds has a nerve ganglion-blocking effect, but it was found that it has no depressant effect on the central nervous system or neuromuscular junction blockade effect, and does not shorten the sleep time induced by pentobarbital sodium in mice.
Image of Da Wei Yao
【Clinical Applications of Da Wei Yao】
1. Treatment of pneumonia, lung abscess, empyema: Use fresh Da Wei Yao whole herb, 100g. Decoct and drink with honey; or grind and squeeze the fresh whole herb, 100-200g, mix with honey and drink.
2. Treatment of acne and abdominal pain: Use fresh Da Wei Yao whole herb, 50-100g. Decoct and drink.
3. Treatment of testicular swelling and pain: Use fresh Da Wei Yao root, 100g. Decoct and drink.
4. Treatment of infantile convulsions: Use dried Da Wei Yao root, 12g, and dried Huangdan herb, 9g. Add a little salt and stew together to drink.
5. Treatment of oral ulcers: Grind the fresh leaves of Da Wei Yao into a paste and gargle with the juice, 4-6 times a day.
6. Treatment of painful abscesses: Use fresh Da Wei Yao root, 100g, and a little salt. Decoct and drink; also take fresh leaves, mash them with cold rice and apply as a poultice.
