Xueshanyizhihao is the rhizome of Aconitum gymnandrum, a plant belonging to the family Ranunculaceae. It is mainly distributed in the Qinghai-Tibet Plateau region of China and is a widely used highly toxic medicinal herb in Tibetan medicine. Let's introduce the main components of Xueshanyizhihao!
Picture of Xueshanyizhihao
[Main components of Xueshanyizhihao]
Aconitine
Alias: Fuzijing
Chemical formula: C34H47NO11
Molecular weight: 645.74
A type of diterpenoid alkaloid. It is found in various plants of the Aconitum genus, such as Aconitum napellus, Aconitum carmichaelii, Aconitum kusnezoffii, and Aconitum taipeicum.
Colorless transparent crystals with a melting point of 204℃ and a specific optical rotation of +19° (chloroform).
Soluble in chloroform, benzene, ethanol, etc.
Aconitine has analgesic effects on various neuralgia and gout, but due to its high toxicity, it is no longer used in clinical medicine.
Chinese medicine and folk remedies widely use various species of Aconitum to relieve fever and pain and treat rheumatism. However, caution must be exercised as Aconitum species often contain aconitine.
[Common emergency treatment methods for Xueshanyizhihao]
1. Induce vomiting.
2. Perform gastric lavage with a 1:5000 potassium permanganate solution.
3. Administer 50mL of 50% sodium sulfate orally as a laxative.
4. For severe vomiting and diarrhea, do not administer a laxative after gastric lavage. Instead, administer 10g of magnesium oxide, 10g of tannic acid, and 20g of medicinal charcoal mixed with warm water as a paste for oral administration. If there is no bowel movement, a 2% saline enema can be used for bowel evacuation.
5. Administer a large dose of atropine to counteract the stimulation of the vagus nerve. The specific dosage depends on the severity of the poisoning. For mild cases, administer subcutaneously or intramuscularly. For severe cases, administer intravenously. The usual dosage is 0.5-1 mg every 2-4 hours. The dosage can be increased and the administration interval can be shortened for severely poisoned patients.
6. Administer 5% or 10% glucose solution to promote the excretion of toxins.
7. If there are symptoms of shock, arrhythmia, seizures, metabolic acidosis, etc., provide symptomatic treatment.
8. For some severe cases, perform blood purification treatment to thoroughly remove toxins from the body.
9. Perform hyperbaric oxygen therapy for patients in the recovery period.
