Understanding the Diverse Effects of Bupleurum in Disease Treatment: A Comprehensive Review

December 29, 2023

Bupleurum is a common traditional Chinese medicine that can be used not only for liver protection but also for treating children's colds. However, understanding the various effects of Bupleurum is essential for its proper application in disease treatment.


1. Antipyretic and Analgesic Effects

Pharmacological research has shown that the volatile oil in Bupleurum has antipyretic effects on both exogenous and endogenous fevers. Additionally, the total saponins in Bupleurum, such as saikosaponin, also have analgesic properties, as demonstrated in the tail-flick test in mice.

2. Hypotensive Effects

Research has shown that Bupleurum contains flavonoids that enhance capillary permeability, resulting in a temporary decrease in blood pressure.

3. Immunomodulatory Effects

The immunomodulatory effects of Bupleurum are attributed to its polysaccharide content, which enhances cellular phagocytosis and helps eliminate invading viruses.

4. Hepatoprotective and Cholagogue Effects

Studies have shown that Bupleurum decoction promotes bile secretion and restores liver function in rats with carbon tetrachloride-induced liver damage, thus exhibiting hepatoprotective and cholagogue effects.

5. Other Effects

In addition to the aforementioned effects, Bupleurum also possesses pharmacological effects such as anti-tumor, anti-radiation, and anti-lipid peroxidation.

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