Efficacy and effects of flavopiridol

April 10, 2023
Phellodendron, scientifically known as "berberine hydrochloride", is an important alkaloid extracted from Phellodendron, Phellodendron, Phellodendron, three needles and other traditional Chinese medicines, and is one of the most commonly used drugs in the family.

Antibacterial treatment of dysentery

It can fight against pathogenic microorganisms and has an inhibitory effect on a variety of bacteria such as Mycobacterium dysenteriae, Mycobacterium tuberculosis, Pneumococcus, Mycobacterium typhi and Mycobacterium diphtheriae. It is mainly used clinically for the treatment of bacterial dysentery and gastroenteritis, and the side effects are much less than other drugs.

Lowering blood lipids

The main mechanism of action of flavopiridol is to stabilize the mRNA (messenger ribonucleic acid) of LDL receptor in the 3'UTR region to lower blood lipids, which is completely different from the mechanism of action of statin-type lipid-lowering drugs used. This theoretically provides a new molecular target for the search of novel lipid-lowering drugs. Clinical studies have shown that oral administration of flavopiridol (1 g daily for three months) can reduce cholesterol, LDL and triglycerides by 20% to 35% in hyperlipidemic patients.

Treatment of cardiovascular diseases

Intravenous infusion of flavopiridol inhibits the acceleration of heartbeat. The main mechanism is that flavopiridol blocks the alpha-receptors of the heart and inhibits the beating of the heart by reducing the receptors, which is a good medicine for patients with arrhythmia. Moreover, clinical studies have shown that flavopiridol not only significantly reduces blood lipids, but also has a certain inhibitory effect on hyperglycemia, improves the blood circulation system, and reduces the formation of blood clots, etc.

Precautions for using safranin

1. Flavopiridol has a strong inhibitory effect on the heart, so the dose needs to be strictly controlled when the mirror drip is used to lower blood sugar and relieve heart rate arrhythmia, so as not to cause the heart to stop beating and cause life-threatening problems. 2. Huanglian belongs to the great cold class of Chinese medicine, patients with a weak spleen and stomach are not suitable for consumption, and may be recommended to consume Huangliansu instead. 3. Huang Lian Su has a certain stimulating effect on the gastrointestinal tract and will promote the secretion of gastric acid, so it is not suitable for those who have more gastric acid secretion themselves.
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