What you can't take with antibiotics

May 8, 2023
Antibiotics are antibacterial drugs that are very effective in treating bacterial infections and diseases. There are strict rules for the use of antibiotics, and the abuse of antibiotics has a great impact on health. So what can't antibiotics be taken together with in general?

What can't cephalosporin be used with

Alcohol

Cephalosporin cannot be taken together with alcohol. The structure of cephalosporin contains tetrathiozole side chain, which will inhibit the activity of acetaldehyde dehydrogenase in liver cells, causing acetaldehyde to be unable to be metabolized by normal oxidation, thus leading to acetaldehyde clustering and causing disulfiram reaction. Symptoms include redness and swelling of the face, dizziness and headache or difficulty in breathing, drop in blood pressure and even shock.

Glucose

When glucose is converted to hepatic glycogen in the liver, a large amount of drug enzymes are released, causing premature destruction of the active ingredients of the drug; at the same time, the alkaline environment of glucose also has a certain degree of damage to the drug.

What foods should not be used with metronidazole

Alcohol

Metronidazole cannot be consumed with alcohol. The intermediate product of alcohol capitalization, acetaldehyde, is toxic, and metronidazole will inhibit the metabolism of acetaldehyde in the body, causing a toxic reaction of acetaldehyde accumulation in the body, manifested as bitterness in the mouth, nausea, vomiting and difficulty in breathing.

Foods high in calcium

Metronidazole should not be eaten with calcium-rich milk, as calcium ions can combine with the drug to produce insoluble precipitates, which destroy the nutritional value of the food and reduce the effectiveness of the drug.

What foods should not be used together with erythromycin

Alkaline food

Erythromycin should not be eaten with foods rich in calcium, phosphorus and magnesium, such as milk, beans, seaweed, fruits, etc. These foods will delay the efficacy and absorption of the drug and reduce the antibacterial effect of the drug.

Alcohols

Erythromycin should not be taken together with alcoholic foods, which can increase the toxicity of erythromycin and damage the liver function.

What foods should not be used together with tetracycline

Tetracycline reacts with metal ions in alkaline food to produce metal complexes that are difficult to absorb, which interferes with the metabolism and absorption of the drug; alkaline food also reacts with gastric acid in the gastric juice to neutralize it, which reduces the solubility of tetracycline and reduces the amount of drug that can be absorbed by the body, making it less effective.

What kind of food should not be used with Kitasamycin

Seafood food is rich in calcium, magnesium, iron phosphorus and other metal ions, which will combine with guitaromycin and easily form substances that are difficult to dissolve and difficult to absorb, reducing the effectiveness of the drug.

What foods should not be used with furazolidone

Alcoholic foods

Furazolidone can inhibit the oxidative decomposition of alcohol and hinder the degradation of acetaldehyde, causing acetaldehyde poisoning reaction.

Tyramine-rich foods

Milk, tofu, chocolate and other foods are rich in tyramine. Furazolidone will inhibit the activity of monoamine oxidase, causing the accumulation of tyramine, causing the body to release endogenous norepinephrine, together with an increase in blood pressure, which may lead to hypertension. Especially for hypertensive patients, special attention must be paid.

Use antibiotics according to medical advice

Improper use of antibiotics can cause damage to the body, and antibiotics must not be used without permission. There are many types of antibiotics and the contraindications to their use go far beyond those mentioned above; there are requirements for the use of antibiotics in special populations such as pregnant women and children; patients suffering from other diseases may also be affected by the use of antibiotics, so it is best to consult your doctor about the safe use of antibiotic types and drug doses.
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