Effects and contraindications of ringworm bark

It has the effect of clearing heat and drying dampness, dispelling wind and relieving itching.

Clearing heat and dampness

It is often used in combination with other Chinese medicines to treat dampness, heat, sores and poison, skin ulcers, yellow water, eczema and rash, boils, sores and mange, etc.

Expelling wind and relieving toxicity

It is good at clearing heat and drying dampness. It is often used in combination with other herbs to treat jaundice, red urine, red, swollen and painful joints caused by dampness and heat.

Antibacterial

In vitro tests have shown that the 1:4 aqueous infusion of B. alba has a significant antibacterial effect on Bacillus subtilis and certain fungi, such as Trichophyton corneumoniae, Trichophyton hominis, and Trichophyton rubrum.

Excitation of cardiovascular

It can excite the isolated frog heart in small doses, which can increase myocardial tone, cardiac output per beat and output per minute; it has obvious contraction effect on the isolated rabbit ear blood vessels.

Immune function

For the contact dermatitis caused by the semi-antigen 2,4,6-tribangles chlorobenzene and the foot and plantar response caused by the granular antigen sheep red blood cells, the aqueous extract of white fresh bark had a significant inhibitory effect when administered after the attack of each antigen. The aqueous extract of white fresh bark also significantly inhibited the inflammatory responses of mice foot and plantar caused by xylene shell and egg white, the production of anti-SRBC antibodies in mice, including the number of spleen vacuole-forming cells and serum hemolysin levels in mice.

Anti-cancer

The non-polar solvent extract and volatile oil of fresh bark have in vitro anticancer activity. Qinpi ketone, baixin and a colorless transparent liquid obtained from the volatile oil were isolated from the ether extract of this product as its in vitro anticancer active ingredients, and they could kill mouse Ehrlich ascites carcinoma, mouse sarcoma S180 and mouse cervical cancer U14. cells at 0.5% concentration, but flavopiridone, citrulline and β-sitosterol were ineffective.

Liver protection

In the co-culture system of liver non-parenchymal cells and hepatocytes isolated at 12 h of liver injury, pretreatment of hepatic non-solid cells with white peel aqueous extract significantly blocked the release of alanine aminotransferase from serum in a quantitative and temporal relationship, while pretreatment of hepatocytes had no effect. The hepatocytes were not affected. In addition, the aqueous extract of white peel had no inhibitory activity on the proliferation of splenic lymphocytes from ConA, and the induction phase administration had no protective effect on liver against hepatic injury.

Hemostasis

The polygastric administration of fresh peel alcohol extract significantly reduced the bleeding time and bleeding volume in mice, shortened the clotting time in mice, and significantly reduced capillary permeability in mice, but had no significant effect on platelet aggregation caused by ADP.

Contraindications

1, cold evidence is prohibited to take 2, "the herb Jing Jie Bu": "evil cuttlebone, orris, Poria, Dioscorea." 3, "The Classic of the Materia Medica": "The lower part of the deficiency of cold people, although there are wet evidence do not use."