The efficacy and effects of snake bed seeds and contraindications and methods of consumption

Pungent, bitter, warm. It is attributed to the Kidney meridian. It mainly treats warming the kidney and helping Yang, dispelling wind, drying dampness and killing worms. It is used to treat impotence in men, itchy scrotum, itchy pubic area in women, cold and infertility in the uterus, rheumatic paralysis, scabies and dampness, etc. The following is a detailed description of the efficacy and contraindications of the seeds of the snake.

Warming the kidney and strengthening the yang

It is used to warm the kidneys and strengthen the yang, for impotence and cold infertility of the uterus, and is often used in combination with the silk, Wu Wei Zi, the efficacy and effects of Baji Tian and Tian Xiong. The "Thousand Gold Formula" has more than 300,000 prescriptions for impotence, and more than half of them are made with Serpentine Seed, which is available for internal and external use.

Kill insects and relieve itching

It is used for scabies, ringworm, rubella and damp itch in the pubic area. It is effective when used alone as a decoction. Combined with the efficacy and effects of bitter ginseng, groundnut, pepper, BaiBu, alum decoction, sitz bath, treat men's scrotal eczema. Women with dampness and toxicity, vulva spasmodic itchy wet rotten, internal use of gentian diarrhea liver soup, external use of this product with bitter ginseng, Wei Ling Xian, the efficacy of angelica tail, water decoction fumigation. For hemorrhoids with unbearable swelling and pain, fumigate with decoction alone. For men with painful swelling and swelling of the pubic area, use the powdered snake bed seeds alone and apply with chicken seeds.

Drying dampness and dispelling wind

Serpentine can dry dampness and dispel wind. It is used for cold and dampness with dampness, and dampness paralysis and lumbago. The former with snake bed seed powder, with an equal amount of alum, the efficacy and effects of vinegar paste pill, such as the bullet large, carmine for the coat, cotton wrapped in the yin, internal use of this product with dogwood meat, with the silk, saxifrage, the efficacy and effects of deer antler, squid bone, etc.. The treatment of cold and damp paralysis and kidney Yang deficiency is particularly suitable, and is often combined with Sang Sang Sang, the efficacy and effects of Eucommia, dog's backbone, Dou Wu, etc.

Treatment of infertility

Serpentine can raise sex hormones in both males and females. It can treat infertility in both males and females. The Compendium of Materia Medica states that it can "warm the yang energy of the husband and help the yin energy of the woman". It can treat male hypogonadism, impotence and premature ejaculation, and can be used with Epimedium and Deer horn tablets, as well as female hypogonadism and infertility, and can be used with Baji Tian and Eucommia. If you feel a large internal fire, it can be used with raw earth and maitong to balance cold and heat.

Anti-allergic

It can treat allergic diseases such as eczema, itchy rash, urticaria, etc. However, these skin diseases are mostly identified by blood-heat and damp-heat, therefore, snake bed seeds need to be used with anti-allergic and anti-allergic herbs that clear heat and cool blood, such as Scutellaria baicalensis, Danpi, Shengdi, etc.

Relaxing smooth muscle spasm

It can treat asthma by relaxing smooth muscle spasm as well as anti-allergy, and is therefore used together with Epimedium and Scutellaria. The effectiveness of Phyllanthus serpentis in treating asthma has not yet attracted clinical attention.

Calming asthma and expectorant

The antispasmodic effect of the total coumarin of Phyllanthus serpentis has direct bronchodilatation, probably through excitation of p receptors. The total coumarin of E. serpentina has a strong expectorant effect. Studies have shown that: C. serpentina has strong bronchodilating effect, and C. serpentina can increase lung perfusion in guinea pigs, and its effect is stronger than that of aminophylline. The gavage of total coumarin of C. serpentina can prolong the duration of asthma attack caused by histamine phosphate and acetylcholine chloride in guinea pigs. In vitro experiments have shown that coumarin has a strong antagonistic effect on histamine-induced tracheal constriction in isolated guinea pigs. The above effects could be blocked by the antidepressant and had no effect on heart rate and blood pressure in anesthetized animals, suggesting that the total coumarin of C. serpentina may selectively excite the β2 receptors on bronchial smooth muscle to produce antispasmodic and antitussive effects. The gavage of total coumarin of C. serpentina to mice can significantly increase the amount of phenol red excretion, suggesting that the product has a strong expectorant effect.

Anti-fungal

The in vitro test of serpentine, bergamot lactone and isothujaplicin has strong activity against the bearded ringworm of S. fungus, and pepper poison phenol has significant anti-mycotic and anti-fungal effect. The in vitro test of S. serpentina infusion has the effect of killing Trichomonas vaginalis, and can be used for the treatment of Trichomonas and mycobacterial infections, with external fumigation as the main treatment.

Anti-arrhythmia

The aqueous extracts of C. serpentina have preventive effects on chloroform-induced ventricular fibrillation in mice, calcium chloride-induced ventricular fibrillation in rats and on ornithine induced arrhythmia in rats, and have obvious therapeutic effects on the latter.

Anesthesia

The aqueous extract of C. serpentina has a blocking anesthetic effect on the isolated sciatic nerve of toads; it has an infiltrative anesthetic effect on guinea pigs and can be enhanced by epinephrine hydrochloride; it has a vertebral canal anesthetic effect on rabbits, but has no surface anesthetic effect on rabbit corneas. It also significantly prolonged the sleep-inducing time of pentobarbital sodium.

Anti-allergic reaction

Serpentine can strongly inhibit passive skin allergic reactions in mice, protect against histaminic wheezing in guinea pigs, significantly antagonize and block the contraction of guinea pig isolated ileum caused by slow-reacting substances and the Schultz-Dzle reaction in guinea pig isolated ileum, and inhibit the degranulation of rat abdominal mast cells. The above effects were all in a dose-dependent manner.

Anti-mutagenic

The aqueous extract of C. serpentina showed strong anti-mutagenic effects by Ames, sister chromatid interchange in isolated cells and chromosomal aberrations in living mouse bone marrow cells and multistained erythrocyte micronuclei test.

Contraceptive

The powdered infusion of C. serpentina was prepared into 20%, 25%, 30%, 35% and 40% suspensions with physiological saline, placed at room temperature for 48 hours, centrifuged at 200 rpm for 10 minutes, the supernatant was filtered and stored at 4℃. The spermicidal effect was observed with the above drug, and it was seen that the spermicidal effect increased with the concentration of the liquid, and the minimum effective concentration of sperm inhibition in 20 seconds was 30%, and the minimum effective dose of sperm inhibition was 250-300 mg per ml of semen mixed with different doses of C. serpentina infusion powder. . Clinical applications 1. Treatment of men with kidney deficiency and impotence and women with infertility, and women with trichomoniasis.

Usage

Serpentine Usage and Dosage

Internal use: decoction, 3-9g; or in pills. For external use: decoction of water for fumigation; or as a sitting medicine (suppository); or powdered and sprinkled, mixed with compresses.

Serpentine dietary supplement

Serpent's bed seed soup Effects: Clearing heat and drying dampness, dispelling wind and relieving itch. Treatment of kidney capsule wind, dry and extremely itchy, like bathing in hot soup, even pimples, shaped like red corn, numb itch, scratching broken immersion lipid water, skin heat pain like fire. Prescription: 15 grams each of Wei Ling Xian, Snake Bedsickle and Angelica Tail, 9 grams of shrunken sand shell, 15 grams each of earth rhubarb and bitter ginseng, and 7 old onion heads. How to use: 1 liter of water, decoction several rolls, pour into a basin, first smoked, waiting for the temperature of the dip wash. Excerpt: 《醫宗金鑑》卷六十九 Bitter ginseng wine with snake bed seeds Effects: Dispelling dampness, detoxifying and relieving itching. Indicated for neurodermatitis, itchy skin, chronic eczema, ringworm, etc. Recipe: 25 grams of snake bed seeds, 25 grams of bitter ginseng, 12 grams of windproof, 12 grams of white fresh skin, 12 grams of alum, 10 grams of Sichuan pepper, 1 catty of 50 degree white wine (or 75% alcohol). Method: Process the above medicines into fine powder, put them in a gauze bag, soak them in wine for 30 days, and shake them frequently. Remove the bag of medicine can be. Dosage: external use. 3 - 4 times a day, using skimmed cotton balls dipped in wine to rub the affected area. Note: This wine is for external use and should not be taken internally. It is more effective if 3 grams of Bambusa, 5 grams of Mucor, and 15 grams of Hibiscus are added to the formula. Snake bed seed porridge Ingredients: 10 grams of snake bed seeds, 50 grams of rice, sugar. Method: Select the snake bed seeds, put them into a pot, add water, soak them for 5-10 minutes and then decoct the juice, add rice and cook the porridge, then mix in sugar when it is cooked and boil it for one or two times. Effects: Warming the kidney and strengthening the yang, drying dampness and killing worms. Indications: Indicated for kidney deficiency and yang atrophy due to deficiency of kidney yang, cold and infertility in the uterus, damp and itchy pubic area, eczema, women's yin cold, cold and dampness with dampness, etc.

Contraindications to the use of Serpentine

It is contraindicated in cases of damp-heat in the lower jiao, or deficiency of kidney yin, easy movement of phase fire, as well as incompetence of the jingguan. 1, "Ben Cao Jing Shu": Do not take if there is fire in the kidney and heat in the lower part of the body. 2. "Ben Jing Feng Yuan": Do not take it if the kidney fire is easily moved and the Yang is strong and the essence is not consolidated. 3. Do not take if there is dampness and heat in the lower jiao, or if the kidney is deficient in yin, and if the phase fire is easily moved and the essence is not solid. 4、《本草经集注》：Evil peony, croton and shellfish. 5, adverse reaction mechanism: the fruit contains volatile oil, which has a slight stimulating effect on the gastrointestinal tract. 6, adverse reactions: dry mouth, drowsiness, stomach discomfort, external use may appear local skin redness, itching.