Efficacy and effects of poria

Poria ling is sweet and light, and is flat. It enters the spleen, kidney and bladder meridians. It has the function of diuretic and dampness permeation, and is mainly used for the treatment of unfavorable urination, edema and fullness, foot odor, diarrhea, gonorrhea, turbidity, banding, etc. Let's take a look at the efficacy and contraindications of Poria ling.

Inducing water and permeating dampness

The drug chemistry said: "pig ling taste light, light main in the ginseng, into the spleen to pass water channels, used to treat water diarrhea wet diarrhea, dampness, drenching, edema, treatment of jaundice. This alone is the most rapid." It is mostly used clinically for treating unfavorable urination, edema and swelling, dampness and dampness, jaundice, foot odor, etc.

Draining heat and quenching thirst

The Compendium of Materia Medica says: "Poria ling is light and permeable, and the gas rises and falls, so it can open the coup and facilitate urination." It is also recorded in the Treatise on Medicinal Properties that "(Poria) relieves the great heat of typhoid fever and epidemic, and generates sweat." Zhang Zhongjing also mentioned in "Treatise on Typhoid Fever", "If the pulse is floating, feverish, thirsty for water, and unhealthy urination, pigling soup is the mainstay.

Treating malaria and stopping diarrhea

This medicine tastes sweet and light, slightly bitter, bitter although down, but sweet and light can percolate and dispersal, ascending and can descend, descending and can ascend, so good at opening the coup to divide the surface of the Yang and the yin of the gas to facilitate the urine, so the former ancient Lord of the malaria in the medium." It is recorded in "The formula of the family treasure" that pig-ling is used with Chai Hu, Fu Ling, Panaxia and ginger to treat new and long-lasting malaria. And the "treatise on the disease of the time - wet diarrhea" cloud: "the disease of diarrhea, belong to the wet for more. Wet dipped in the spleen, the spleen loss of health, can not permeate, to the appendage does not grasp the clear and other turbid, water and grain into the large intestine and diarrhea carry on. The treatment of diarrhea, "Introduction to Medicine. Diarrhea" in the cloud: "At first, it is appropriate to divide the middle Jiao, permeate the lower Jiao." Therefore, the treatment of diarrhea with Poria can be divided into urine and stool, so that the dampness goes to the diarrhea from the stop.

Diuretic

In a healthy person taking 8g of Poria decoction (4 times), the urine volume and chloride in urine increased by 62% and 54.5% respectively in 6 hours, which is stronger than caffeine, mucuna pruriens or poria. Wu Ling San (Poria, Poria, Atractylodes, Zedoary, and Cinnamomum) was injected quietly in dogs, and the well increased the excretion of sodium, potassium, and chloride ions while increasing the urine volume. The diuretic mechanism may be the inhibition of renal tubular reabsorption of electrolytes and water.

Improving immunity

The extract can increase the phagocytosis of reticuloendothelial system in mice, resulting in increased formation of antibody cells in the spleen and increased conversion of T lymphocytes. Intraperitoneal injection of Poria polysaccharide can significantly increase the admixture of 3H-TdR in mouse thymocytes and accelerate the release of thymocytes at the same time. It could significantly increase the antibody-forming cells in the spleen of tumor-bearing mice, improve the phagocytic ability of abdominal macrophages and promote the production of IgM antibodies. It has a significant increase in dispersed ANAF-positive lymphocytes and a significant protective effect against immune system suppression caused by antitumor chemical drugs. It can improve the conversion rate of T lymphocytes and the phagocytosis of macrophages.

Anti-tumor

Anticancer effect of Poria polysaccharide. The aqueous soluble fraction of Poria lanceolata was injected intraperitoneally 2g (raw drug)/kg per day for 10 days, and the inhibition rate of sarcoma 180 in mice was 62%, and the tumor suppression rate of liver cancer in mice was 37%~54%; but mouse leukemia L615 was not effective.

Enhance the function of secretion system

Poria polysaccharide can increase the cortisol content in the plasma of animals significantly, but animals after removal of adrenal glands do not show changes, so it is believed that its effect is through the adrenal glands.

Anti-tumor

Poria extract or alcoholic water soluble fraction can enhance the phagocytosis of mouse reticuloendothelial system, which suggests that Poria is a non-specific immunostimulant. Its tumor suppressive effect may also be related to this.

Anti-radiation

Poria polysaccharide has obvious effect in preventing acute radiation sickness in mice, with wide effective agent and time. Experiment: Intraperitoneal injection of mice subjected to lethal dose (800 rad) of total body irradiation 2 and 48 hours before irradiation, respectively, increased their survival rate by 30-70%. Post-irradiation administration, either orally or intraperitoneally, had protective efficacy, and the preventive effect was higher than the therapeutic one. Poria polysaccharide did not protect the hematopoietic function of the irradiated mice, but did significantly improve the stress function of the adrenal cortex of the irradiated mice. It is tentatively suggested that the anti-radiation effect of Poria polysaccharide may be through regulating the function of pituitary-adrenal system to put the body in a stressful state, thus enhancing the ability to resist radiation damage.

Other effects

Poria has also antibacterial and antiradiation effects. It has a protective effect on the liver and liver glycogen depletion, and can reduce the lethal toxicity caused by methotrexate. In hepatitis patients, it has the effect of decreasing GPT and TTT and turning HBsA9 negative.

The contraindications of consuming poria

1, no water and moisture people should not take poria "Medical Qiyuan": "poria light ooze, big dry dead fluid, no wet evidence do not take." 2, there is a wet disease and kidney deficiency is contraindicated pig ling. "Introduction to Medicine": "There are dampness and kidney deficiency is contraindicated." 3, faint eyes, no dampness and thirst, the two are prohibited poria. The "with this herb": "eyes faint, no dampness and thirst, the two are prohibited.