The efficacy and effects of perilla leaves and contraindications

March 30, 2023
Perilla leaf is warm in nature, pungent in taste, and belongs to the spleen and lung meridian, it is a common herb in Chinese medicine, and is one of the frequently used ingredients on our table, but what are the specific effects and contraindications of perilla leaf?

Antipyretic and sedative

Perilla aldehyde isolated from perilla leaves has a sedative effect and can prolong the sleep time of rats with reduced phenobarbital. In addition, the decoction and infusion of perilla leaves 2g/kg orally administered to rabbits with mixed typhoid vaccine fever had a weak antipyretic effect.

Antibacterial

Perilla oil has obvious inhibitory power against naturally contaminated moulds, and its inhibitory power against moulds is significantly better than that of nipagin acetic acid, and it has the characteristics of low dosage, safety and not affected by pH factor.

Raise blood sugar

Experiment shows that perilla oil 0.35ml/kg given orally to rabbits can make blood sugar rise; the main component of the oil, perilla aldehyde, made into oxime, has stronger effect on raising blood sugar than perilla oil.

Promote intestinal motility

In the experiment, Perilla ketone, isolated from perilla leaves, has the effect of promoting intestinal peristalsis in rats, which accelerates the movement of substances in their intestines. Therefore, eating some perilla leaves in moderation can help digestion.

Anti-cancer

Perilla oil can significantly restrain the incidence of cancer caused by chemical carcinogens, reduce the size of tumors and extend the time of tumor appearance. The effect of feeding chemical carcinogen-induced colorectal cancer rats with perilla oil is that perilla oil can reduce the activity of mucosal ornithine decarboxylase, reduce the sensitivity of colon muscle to tumor promoter - colon epithelial cell phospholipid membrane, and effectively restrain colon cancer.

Anti-allergy

It has been tested that perilla leaves are rich in vitamin C, potassium and iron, and also rich in unsaturated fatty acids, which have the effect of normalizing immune function and moderating allergic reactions such as allergic dermatitis and hay fever. Studies have also found that the medicinal effects of the sage stalk are similar to those of the sage leaf, and the sage stalk can also be used in the treatment of skin diseases.

Anti-thrombotic

Experiments have confirmed that perilla oil can inhibit the free radicals of platelets and serotonin, thus inhibiting the occurrence of thrombosis and having an antithrombotic effect. α-linolenic acid and other unsaturated fatty acids have the effect of lowering platelet AA levels and inhibiting thromboxane A1 production, which can weaken platelet activity and effectively control and inhibit platelet agglutination in the vessel wall, thus reducing the formation of thrombosis.

Memory enhancement

Animal experiments have shown that perilla oil can promote the synthesis of nucleic acid and protein in the brain of mice, regulate the level of monoamine neuromediators in the brain of mice, which can significantly reduce the number of mice skipping, significantly increase the correct rate of water maze test and shorten the time to reach the end point, and enhance the retinal reflexes of rats, and significantly increase the correct response rate to luminance discrimination learning experiments. In other words, the consumption of perilla leaves is beneficial to improve human memory ability.

Relieving cough and asthma

Some of the acids in perilla leaves can relieve smooth muscle spasms and calm asthma; in addition, in the anti-allergic process, it can also reduce inflammatory reactions and so on, and play a role in relieving cough and asthma.

Others

The linolenic acid in the sage is one of the effective ingredients to lower blood lipids; the flavonoids in the sage can fight against oxygen free radicals and superoxide anions, which has an anti-aging effect; if bitten by mosquitoes, you can also mash fresh sage leaves and put them on to relieve pain and itching; sage can also treat bad breath, which is better than chewing gum, and sage and dahurica are put together to treat bad breath.

Contraindications of perilla leaves

Although perilla has more effects, but if perilla leaves are consumed together with carp, it is easy to produce poisonous sores. People suffering from qi deficiency, yin deficiency and warm diseases should not consume perilla leaves either. Also, perilla leaves should not be consumed too much because they contain a lot of oxalic acid, which produces calcium oxalate and zinc oxalate when it meets calcium and zinc in the human body, which can damage the nerves, digestive system and hematopoietic function.
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